We are actively seeking a postdoctoral fellow! Please contact Dr. Yokom if interested
Molecular Biology and Biochemistry - Our foundation is rooted in understanding the molecules which govern life as we know it (and learning what we dont know). This is fundamentally connected to molecular biology and using in vitro purification techniques to isolate autophagy components to investigate function.
Movie of TECPR1 alone in an elongated hook conformation
Structural Biology- Resolving biological molecules via cryo electron microcopy, electron tomography and x-ray crystallography give a 'seeing is believing' feel to understanding how biological molecules directly interact to perform cellular functions including signaling, scaffolds and remodeling of membranes.
Our group is pioneering cryo FIB-SEM techniques to expanded the scale of structural biology we can perform. This includes using the Aquilos 2 and Thunder systems at the NextGen Precision health Institute.
Cell Biology- Development of cell biological assays to monitor autophagy tethering and fusion. We utilize fixed and live cell imaging to dissect the interactions of critcial proteins.
We are actively looking for researchers experienced in cell biology or interested in learning it!