Publications

Assistant Professor (2023-present)

Still to come!

Postdoctoral (2017-2022)

University of California, Berkeley

Ren X., Nguyen T.N., Wai Kit Lam, Buffalo C.Z., Lazarou M., Yokom A. L. +, Hurley J.H.+ Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation. Science Advances 

Preprint on Biorxiv 

Yokom, A. L.*, Shi, X.*, Chang, C.*, Jensen, L. E. & Hurley, J. H. The autophagy adaptor NDP52 and the FIP200 coiled-coil allosterically activate ULK1 complex membrane recruitment. eLife (2020). [*co-first authors]

Preprint on Biorxiv

Yokom A.L.*, Shi X* Wang C, Young L.N., Youle R.J., Hurley J.H. ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer. Journal of Cell Biology (2020). [*co-first authors]

Preprint on Biorxiv

Yokom A.L.*, Horst B.G.*, Rosenberg D.J., Morris K.L., Hammel M., Hurley J.H., Marletta M.A. Allosteric activation of the nitric oxide receptor soluble guanylate cyclase mapped by cryo-electron microscopy. eLife. (2019). [*co-first authors]

Preprint on Biorxiv

Doctoral Work (2012-2017)

University of Michigan 

Yokom A.L.*, Gates S.N.*, Lin J., Jackrel M.E., Rizo A.N., Kendsersky N.M., Buell C.E., Sweeny E.A., Chuang E., Torrente M.P., Mack K.L., Su M., Shorter J., Southworth D.R. Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science (2017). [*co-first authors]

Yokom A.L., Gates S.N., Jackrel M.E., Mack K.L., Su M., Shorter J., Southworth D.R. Spiral architecture of the Hsp104disaggregase reveals the basis for polypeptide translocation. Nature Structural and Molecular Biology. (2016).

News and Views - Written by Steven Gylnn and Peter Chien

Yokom A.L., Morishima Y., Lau M., Su M., Glukhova A., Osawa Y., Southworth D.R., Architecture of the Nitric Oxide Synthase Holoenzyme Reveals Large Conformational Changes and a Calmodulin-Driven Release of the FMN Domain. Journal of Biological Chemistry. (2014).

Selected for Paper of the Week and Cover Illustration

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